Ledermycin

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How does it work?

Demeclocycline hydrochloride belongs to a group of antibiotics called tetracyclines. It is an antibiotic which has the ability to inhibit the growth of a wide variety of bacteria. It interferes with the production of proteins that the bacteria need to multiply and divide. This inhibits the ability of the bacteria to grow (bacteriostatic) and therefore stops the spread of the infection.

What is it used for?

- Acne vulgaris
- Chronic bronchitis
- Dental infections
- Disease caused by infection with Leptospira bacteria (Weil's Disease/leptospirosis)
- Excess secretion of antidiuretic hormone, called syndrome of inappropriate antidiuretic hormone (SIADH)
- Infection caused by Brucella bacteria (brucellosis)
- Infections caused by Rickettsiae micro-organisms transmitted by lice, fleas, ticks and mites
- Infections of the sex organs and organs associated with urination (genito-urinary infections)
- Lyme disease

Use with caution in

- Kidney disease
- Liver disease

Not to be used in

- Children under 12 years of age
- Long-term inflammation of skin and some internal organs (systemic lupus erythematosus)
- Severe kidney disease

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

- This medicine should not be used in pregnancy. Seek medical advice from your doctor.
- Significant amounts of this medicine may pass into breast milk. It should not be used by breastfeeding mothers. Discuss this with your doctor.

Label warnings

- Avoid exposure of skin to direct sunlight or sun lamps.
- Do not take iron preparations, milk or indigestion remedies at the same time of day as this medication.
- Take at regular intervals. Complete the prescribed course unless otherwise directed.
- Take this medication an hour before food or on an empty stomach.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine.

Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

- Headache
- Rash
- Diarrhoea
- Visual disturbances
- Inflammation of the pancreas (pancreatitis)
- Abnormal reaction of the skin to light, usually a rash (photosensitivity)
- Inflammation of the large intestine (colitis)
- Damage to the liver
- Reversible excessive thirst and urine production due to lack of a horone acting on the kidney(diabetes insipidus)
- Nausea and vomiting

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. . For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

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