Imazin XL (discontinued in the UK- September 2005)

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Headache

Rash

Blood disorders

Indigestion (dyspepsia)

Severe swelling of lips, face or tongue (angioedema)

Dizziness

Flushing

Breathing difficulties due to a narrowing of the airways (bronchospasm)

Irritation to the lining or movements of the gut

Bleeding from the stomach or intestine

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

Sildenafil (viagra) should not be taken with this medicine as it can cause a large, sudden drop in blood pressure with dizziness and fainting, and may also decrease the blood supply to the heart, causing a heart attack. Aspirin increases the effect of blood-thinning or anti-clotting medicines such as warfarin. Therefore, unless treatment is started by a doctor, with careful adjustment of the anticoagulant dose, the two should not be taken together. Aspirin reduces the rate at which the body can remove the medicine methotrexate. The two should not usually be used together. Imazin should not be used within 8-12 days of taking mifepristone as aspirin may reduce its effectiveness. Except when used at a low dosage for anti-clotting purposes, aspirin should not be taken with any other non-steroidal anti-inflammatory drug (NSAID) due to an increased risk of stomach ulceration and bleeding. When aspirin is taken with corticosteroids there is an increased risk of stomach ulceration and bleeding. Aspirin can prevent the action of certain medicines for gout, such as probenecid and sulfinpyrazone. Aspirin may reduce the effect of some medicines for lowering high blood pressure, for example, ACE inhibitors such as enalapril. Isosorbide mononitrate may enhance the blood pressure lowering effects of medicines for high blood pressure.

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