How does it work?
Hydrocortisone is a type of medicine known as a corticosteroid. Corticosteroids are hormones produced naturally by the adrenal glands which have many important functions on every organ system.
Corticosteroids affect the strength of heart muscle and its response to natural chemicals affecting heart rate. They affect the water and salt balance in the body and also enable the body to cope with stress. Stress includes changes in temperature, pain, fear, anxiety and illness and can be hazardous if the body is not equiped to cope, due to low levels of corticosteroids. Corticosteroids allow us to respond to stress by increasing the rate and force of the heartbeat, increasing blood supply to essential tissues (muscle, heart, brain), increasing the body's supply of energy by raising blood sugar and by several other effects on body systems.
Hydrocortisone is used as replacement therapy in people whose adrenal glands are not producing enough natural corticosteroids (adrenal insufficiency). This can be due to disease (Addison's disease), surgical removal of the adrenal gland(s) or damage to the adrenal glands. Low blood levels of corticosteroids must be treated with replacement therapy to allow the body to function normally.
What is it used for?
Insufficient production of natural steroid hormones by the adrenal glands (adrenal insufficiency)
Warning!
Corticosteroid medicines taken by mouth should be taken in the morning to mimic the natural production of corticosteroids by the body. They should be taken after food.
If you are taking a corticosteroid for longer than three weeks you will usually be given a steroid card with your medicine. The card contains details of your prescriber, type of steroid, dose taken and the duration of treatment. It's purpose is to act as reminder that your medicine should not be stopped suddenly, and to provide information of your treatment in case of an accident. You should carry it with you at all times and show it to anyone who treats you (eg doctor, nurse, pharmacist, dentist).
If you are taking this medicine long-term, your doctor may need to temporarily increase your dose if you experience any any additional illness, trauma or surgery during treatment. Discuss this with your doctor.
You should not stop taking this medicine suddenly, particularly if you have been taking it for longer than 3 weeks. This is because long-term use of the medicine suppresses the natural production of corticosteroids by the adrenal glands. This means that the body becomes temporarily reliant on the medicine. When it is time to stop treatment the dose should be tapered down gradually, to allow the adrenal glands to start producing adequate amounts of natural steroids again. Follow the instructions given by your doctor or pharmacist.
This medicine may increase your susceptibility to infections and also mask the symptoms of these infections. Consult your doctor if you get an infection during treatment.
This medicine may reduce the secretion of steroid hormones in the body normally responsible for fluid and salt balance. A replacement steroid (mineralocorticoid) and/or salt should be taken with this medicine.
This medicine may interfere with the results of laboratory tests for certain bacterial infections.
Use with caution in
Abnormal muscle weakness
Adolescents
Children
Decreased kidney function
Diabetes
Elderly people
Family history of diabetes
Family history of glaucoma
Glaucoma
Heart failure
Herpes simplex virus infection of the eye
High blood pressure
Hypothyroidism
Inflammation of small sac-like structures which sometimes form in the walls of the intestine (diverticulitis)
Inflammation of the bowel and back passage
Inflammatory bowel disease such as ulcerative colitis or Crohn's disease
Liver cirrhosis
Osteoporosis
People who have recently had a heart attack
Peptic ulcer
Post-menopausal women
Previous muscle disease (myopathy) caused by steroids
Recent surgical procedure involving the joining together of ends of the intestine after a section has been removed (intestinal anastomosis)
Tuberculosis
Not to be used in
Fungal infection throughout the body (systemic fungal infection)
Protozoal infection of the intestine
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
This medicine is not recommended for use in pregnancy unless considered essential by your doctor. Seek medical advice from your doctor.
The safety of this medicine during breastfeeding has not been established. Seek medical advice from your doctor.
Label warnings
Follow the printed instructions you have been given with this medication.
Take this medication with or after food.
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