Hyalase

How does it work?

Hyaluronidase is an enzyme that temporarily and reversibly breaks down the polysaccharide, hyaluronic acid, which is found between the cells of connective tissue. Hyaluronic acid may be thought of as the "glue" that holds cells together. Hyaluronidase improves the penetration of subcutaneous or intramuscular injections. Hyaluronidase can also be used to speed up the rate at which the body resorbs excess blood and fluids. For example, blisters or haematomas (large bruises). Hyaluronidase is often administered at the same time as other injections, such as local anaesthetics, where fast penetration desirable.

What is it used for?

Enhanced permeation of intramuscular or subcutaneous injections.

Resorption of excess fluids and blood in the tissues.

Use with caution in

Do not not apply directly to the eye

Infants and elderly

Not for use in intravenous injection

Not to be used in

Avoid sites of infection or cancer

Known sensitivity or allergy to any ingredient

Premature labour

Reduction in the swelling caused by bites or stings

This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor or pharmacist immediately.

Pregnancy and Breastfeeding

Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.

This medicine should be avoided during pregnancy. Seek medical advice from your doctor.

This medicine should be used with caution by breastfeeding mothers, and only if the expected benefit to the mother is greater than any possible risk to the baby. Seek medical advice from your doctor.

Side effects

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect.

Irritation in area of use

Bruising or pain at injection site

Excessive fluid retention in the body tissues, resulting in swelling (oedema)

Bleeding at injection site

Allergic reaction to active ingredient

The side effects listed above may not include all of the side effects reported by the drug's manufacturer. For more information about any other possible risks associated with this medicine, please read the information provided with the medicine or consult your doctor or pharmacist.

How can this medicine affect other medicines?

There are no known interactions.

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