Fragmin

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines while having treatment with this one, to ensure that the combination is safe.

There may be an increased anti-blood-clotting effect, which can result in an increased risk of bleeding or increased time taken to stop bleeding, if this medicine is used in combination with any of the following medicines:

- antiplatelet ('blood-thinning') medicines, such as aspirin, dipyridamole, clopidogrel
- clot-busting medicines (fibrinolytics) such as streptokinase, alteplase
- non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, diclofenac, naproxen
- oral anticoagulants, such as warfarin, nicoumalone, phenindione
- probenecid.

Your doctor or pharmacist will adjust the doses of your medicines so that the appropriate effect on your blood clotting time is achieved.

There may be an increased risk of a rise in the amount of potassium in your blood if this medicine is used in combination with any of the following medicines:

- ACE inhibitors, eg captopril, lisinopril
- ciclosporin
- potassium-sparing diuretics, eg spironolactone, triamterene, amiloride
- potassium supplements
- potassium-containing salt substitutes.

The amount of potassium in your blood should be regularly monitored if you are taking any of these during treatment with this medicine.

Other medicines containing the same active ingredient

There are currently no other medicines available in the UK that contain dalteparin as the active ingredient.

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