Health Centres - Fortral
How does it work?
Pentazocine belongs to a group of medicines called opioids. Opioids mimic the effects of naturally occurring pain reducing chemicals (endorphins). They combine with the opioid receptors in the brain and block the transmission of pain signals. Therefore, even though the cause of the pain may remain, less pain is actually felt.
What is it used for?
- Moderate to severe pain
Warning!
- This medicine may cause drowsiness. If affected do not drive or operate machinery.
Use with caution in
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Asthma
- Breathing problems
- Cholecystitis - inflammation of the gall bladder.
- Decreased kidney function
- Decreased liver function
- Elderly people
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Enlarged prostate gland
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Epilepsy
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High blood pressure
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Hypothyroidism
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Inflammation of pancreas
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Inflammatory bowel disease such as ulcerative colitis or Crohn's disease
- Insufficient production of natural steroid hormones by the adrenal glands (adrenal insufficiency)
- Life long inherited blood diseases which can cause a variety of symptoms, including mental health problems (porphyrias)
- Low blood pressure (hypotension)
- People currently taking monoamine-oxidase inhibitor (MAOI) antidepressants
- The period immediately following a heart attack (acute phase - myocardial infarction)
Not to be used in
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Alcoholism
- Head injury
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Heart failure
- Increased pressure in the brain (raised intracranial pressure)
- Known sensitivity or allergy to any ingredient
- Slow, shallow breathing (respiratory depression)
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Sudden asthma attack
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Pregnancy and Breastfeeding
Certain medicines should not be used during pregnancy or breastfeeding. However, other medicines may be safely used in pregnancy or breastfeeding providing the benefits to the mother outweigh the risks to the unborn baby. Always inform your doctor if you are pregnant or planning a pregnancy, before using any medicine.
- The safety of this medicine during pregnancy has not been established. Seek medical advice from your doctor.
- This medicine should be used with caution by breastfeeding mothers, and only if the expected benefit to the mother is greater than any possible risk to the baby. Seek medical advice from your doctor.
Side effects
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine.

