Health Centres - Adult meltus chesty coughs with congestion
How does it work?
Adult meltus chesty coughs with congestion linctus contains two active ingredients, guaifenesin and pseudoephedrine hydrochloride.
Guaifenesin is a type of medicine called a cough expectorant. Expectorants are used to treat a productive or chesty cough, in which phlegm is coughed up.
Expectorants such as guaifenesin are thought to work by stimulating receptors in the stomach, causing a reflex increase in the volume of fluid produced in the airways. This decreases the thickness of the secretions in the airways, thus loosening phlegm and making it easier to cough up.
Pseudoephedrine is a type of medicine called a decongestant. It works by acting on alpha receptors that are found in the walls of blood vessels in the linings of the nasal passages and sinuses. It causes these blood vessels to contract and narrow, thereby decreasing blood flow into the linings of the nose and sinuses. This reduces the feeling of congestion and also reduces the production of mucus.
Pseudoephedrine also has a weak effect on receptors in the lungs called beta 2 receptors. By acting on these receptors it causes the muscles in the airways to relax. This allows the airways to open, making breathing easier.
The combination of guaifenesin and pseudoephedrine in this medicine may be useful for relieving chesty coughs with associated nasal or sinus congestion.
What is it used for?
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Chesty coughs and nasal congestion, eg associated with colds.
Warning!
- Do not exceed the recommended dose. If symptoms persist consult your doctor.
- If you have any of the following symptoms you should consult your doctor so that your cough can be investigated further: coughing up phlegm that is green, rusty brown, yellow, blood-stained or foul smelling; shortness of breath, wheezing or difficulty breathing; chest pain; pain and swelling in your calf; sudden weight loss; recurrent night-time cough; or a long-term persistent cough.
Use with caution in
- Decreased kidney function
- Decreased liver function
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Disease involving the heart and blood vessels
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High blood pressure
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Overactive thyroid gland
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Enlarged prostate gland
- Difficulty passing urine (urinary retention)
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Diabetes
- Raised pressure in the eye ball, eg glaucoma.
Not to be used in
- Children under 12 years of age
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Very high blood pressure
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Severe coronary artery disease
- People who have taken a monoamine-oxidase inhibitor antidepressant (MAOI) in the last 14 days.
This medicine should not be used if you are allergic to one or any of its ingredients. Please inform your doctor or pharmacist if you have previously experienced such an allergy.
Pregnancy and Breastfeeding

