Campto

How can this medicine affect other medicines?

It is important to tell your doctor or pharmacist what medicines you are already taking, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before taking any new medicines during treatment this one, to ensure that the combination is safe.

The herbal remedy St John's wort (Hypericum perforatum) should not be taken by people having treatment with this medicine. This is because St John's wort may make this medicine less effective.

The manufacturer recommends that the following medicines should be avoided in people having treatment with irinotecan, as they may also make it less effective:

carbamazepine

phenobarbital

phenytoin

rifampicin.

The manufacturer recommends that ketoconazole should be avoided in people having treatment with irinotecan, as it may increase the risk of side effects.

Chemotherapy decreases the body's immune response. This means that vaccines may be less effective if given during treatment, and live vaccines may cause serious infections. Live vaccines include: measles, mumps, rubella, MMR, oral polio, oral typhoid and yellow fever. If live vaccines are needed they should be postponed until at least six months after finishing chemotherapy.

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