How can this medicine affect other medicines?
You should tell your doctor what medicines you are taking, including those bought without a prescription and herbal medicines, before you start your chemotherapy. Likewise, always check with your doctor or pharmacist before taking any new medicines during your treatment.
There may be an increased risk of side effects if this medicine is used with other anticancer medicines.
High doses of ciclosporin increase the blood level and risk of side effects of doxorubicin.
Barbiturates such as phenobarbital may reduce the effects of doxorubicin.
Some cytotoxic anticancer medicines can reduce the blood levels of some antiepileptic medicines, therefore if doxorubicin is given to people taking antiepileptics, the blood levels of these medicines should be monitored so that seizures can be prevented.
Some anticancer medicines can increase the blood-thinning effect of anticoagulants such as warfarin, therefore if doxorubicin is given to people taking warfarin, blood clotting times (INR) should be monitored.
Vaccines may be less effective in people receiving chemotherapy. This is because chemotherapy medicines reduce the activity of the immune system and can prevent the body forming adequate antibodies. Live vaccines should be postponed until at least six months after finishing chemotherapy because they may cause infection. Live vaccines include the following: oral polio; rubella; measles, mumps and rubella (MMR); BCG; yellow fever and oral typhoid vaccines.
Other medicines containing the same active ingredients
| Doxorubicin hydrochloride (liposomal) |
Doxorubicin hydrochloride |
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