Alphagan (brimonidine)

How can this medicine affect other medicines?

The brimonidine in these eye drops could be absorbed into the bloodstream in low amounts after application to the eye and it could therefore interact with other medicines that you are taking by mouth, injection, skin patch or suppository. You should tell your doctor or pharmacist what medicines you are already using, including those bought without a prescription and herbal medicines, before you start treatment with this medicine. Similarly, check with your doctor or pharmacist before starting any new medicines while using this one, to ensure that the combination is safe.

If you are using more than one type of eye drop you should administer them at least five minutes apart, to prevent the second drop washing away the first. Use eye gels or ointments last.

The manufacturer states that these eye drops should not be used by people taking any of the following medicines:

monoamine oxidase inhibitor (MAOIs), eg the antidepressants phenelzine, tranylcypromine or isocarboxacid

tricyclic antidepressants, eg amitriptyline, imipramine

related antidepressants, eg mianserin.

Other medicines containing the same active ingredient

There are currently no other medicines available in the UK that contain brimonidine as the sole active ingredient.

Combigan eye drops contain brimonidine in combination with the beta-blocker medicine timolol.

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