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Typhoid fever and paratyphoid fever

Health and Nutrition > Diseases > T

Typhoid fever and paratyphoid fever (Contd)

Written by Dr Charlie Easmon, specialist adviser in travel medicine

What can you do yourself?

  • There are several forms of vaccine that protect against Salmonella typhi. Most travel clinics use the injectable form (Typherix or Typhim Vi) rather than the oral form (Vivotif). The injectable vaccine is easier to administer since it only requires one dose and has less side effects. It should be administered at least two weeks prior to potential typhoid exposure and is effective for three years.
  • The routes of infection depend on hygiene conditions and general kitchen hygiene should be maintained to prevent infection. For travel, the same precautions can be taken as described under cholera.
  • How is the disease diagnosed?
    The clinical picture together with information on travel may be a good pointer for the doctor in moderate to severe cases. For the final diagnosis to be established, the bacteria have to be detected in samples from the stool, blood or other tissue.

    Malaria also needs to be considered as another possible explanation for the symptoms of the disease when the patient has been travelling in a malarial area.

    How is typhoid fever treated?
    Treatment requires admission to hospital and loss of fluid and salt is treated with fluid therapy as appropriate.

    The bacterium is controlled with antibiotics, and in very rare cases steroid medicines are also included in the treatment.

    Prevention
    Within the hospital setting, infected people are cared for in isolation. Proper hand hygiene is the most important way of preventing further spread in hospital.

    Stool samples are also taken from members of the patient's family to identify any 'healthy' carriers.



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