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Why should a child take the medication?
It is often both necessary and helpful to give children medication because it can:
Which medication should my child use?
Medicines for asthma are generally thought of in two main groups:
These drugs (and the other inhaled drugs mentioned below) are inhaled from a variety of delivery devices, the most familiar being the pressurised metered-dose-inhaler. Special adaptors and types of inhaler are available to make it easier to administer inhaled medication to young children. A doctor or practice nurse can recommend which type will be the most suitable.
Longer-acting beta 2 agonists include salmeterol. Their action lasts over 12 hours, making them suitable for twice daily dosage. These medications are particularly good for exercise-induced problems and night-time symptoms. They are not suitable for very young children.
Anticholinergics
Theophylline
Preventers
Cromones
Leukotriene receptor antagonists
What are the long-term prospects?
One of the ways in which the size of the airways is naturally controlled is through nerves that connect to the muscles. The nerve impulses cause the muscles to contract, thus narrowing the airway. Anticholinergic drugs block this effect, allowing the airway to open. The size of this effect is fairly small, so it is most noticeable if the airways have already been narrowed by other conditions, such as chronic bronchitis. These drugs are therefore not commonly used in children, but ipratropium is available for use in children if required.
Theophylline and aminophylline are given by mouth and are less commonly used in Britain because they are more likely to give side effects than inhaled treatment. They are still in very wide use throughout the world.
There are three main groups of these.
There are two drugs in this group: sodium cromoglicate and nedocromil sodium. They also act to reduce airway inflammation. They tend to be best for mild asthma and are more effective in children than adults. The drugs are given by inhalation and usually very well tolerated. This is a good first-line preventative treatment in children, but may take up to six weeks to have an effect.
Leukotrienes are compounds released by inflammatory cells within the lung and which have a powerful constricting effect upon the airways. By blocking this effect with these antagonist drugs the constriction is reversed. One of these drugs, montelukast, is presently licensed for children over two years old. Zafirlukast
can be used in children over 12 years old.
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