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Asthma and children

Health and Nutrition > Diseases > A

  Asthma and children  © NetDoctor/Geir Haukursson
Asthma and children (Contd)

Reviewed by Dr Stuart Crisp, paediatric specialist registrar and Dr Stephen Greene, consultant paediatrician

How does the doctor decide whether a child has asthma or not?

  • By listening to the symptoms described by parent and child.
  • By examining the child by listening to their chest using a stethoscope.
  • By measuring the capacity of your child's lungs with a peak flow monitor - a simple device that measures the maximum speed at which the child can blow out. The reading is reduced if the airways are tight. This can be done at home or in the doctor's surgery.
  • By checking whether the treatment recommended by the doctor works.
  • Why should a child take the medication?
    It is often both necessary and helpful to give children medication because it can:

  • remove their symptoms allowing them to play and exercise again, like other children.
  • subdue the allergic reaction of their body and reduce the inflammation in the airways.
  • remove or lessen damaging effects on your child's lungs so they develop naturally.
  • Which medication should my child use?
    Medicines for asthma are generally thought of in two main groups:

  • relievers (bronchodilators): these are quick-acting drugs that relax the muscles of the airways. They relieve the symptoms of wheeze, cough and breathlessness and are the first-line treatment of an acute asthmatic attack.
  • preventers (anti-inflammatories): these act over a longer time and work by reducing the inflammation within the airways.
  • Relievers There are three groups of these. All three types of reliever can be combined if necessary.

    Beta 2 agonists These drugs act on molecule-sized receptors on the muscle of the bronchioles. The drug fits the receptor like a key fits a lock and stimulates the muscle to relax. Examples of those that act for a short time (three or four hours following a single dose) are salbutamol and terbutaline.

    These drugs (and the other inhaled drugs mentioned below) are inhaled from a variety of delivery devices, the most familiar being the pressurised metered-dose-inhaler. Special adaptors and types of inhaler are available to make it easier to administer inhaled medication to young children. A doctor or practice nurse can recommend which type will be the most suitable.

    Longer-acting beta 2 agonists include salmeterol. Their action lasts over 12 hours, making them suitable for twice daily dosage. These medications are particularly good for exercise-induced problems and night-time symptoms. They are not suitable for very young children.

    Anticholinergics
    One of the ways in which the size of the airways is naturally controlled is through nerves that connect to the muscles. The nerve impulses cause the muscles to contract, thus narrowing the airway. Anticholinergic drugs block this effect, allowing the airway to open. The size of this effect is fairly small, so it is most noticeable if the airways have already been narrowed by other conditions, such as chronic bronchitis. These drugs are therefore not commonly used in children, but ipratropium is available for use in children if required.

    Theophylline
    Theophylline and aminophylline are given by mouth and are less commonly used in Britain because they are more likely to give side effects than inhaled treatment. They are still in very wide use throughout the world.

    Preventers
    There are three main groups of these.

    Corticosteroids Corticosteroids, budesonide and fluticasone have made an enormous difference to the management of asthma. They work to reduce the amount of inflammation within the airways, reducing their tendency to contract and have allowed many people with previously troublesome asthma to lead almost symptom-free lives. They are usually given as inhaled treatment, although sometimes short courses of oral steroid tablets may be required for bad attacks. Although steroids are powerful drugs with many potential side effects, their safety in asthma has been well established. It is also important to balance the problems that arise from poorly treated asthma against the improvement in health that occurs when the condition is well treated.

    Cromones
    There are two drugs in this group: sodium cromoglicate and nedocromil sodium. They also act to reduce airway inflammation. They tend to be best for mild asthma and are more effective in children than adults. The drugs are given by inhalation and usually very well tolerated. This is a good first-line preventative treatment in children, but may take up to six weeks to have an effect.

    Leukotriene receptor antagonists
    Leukotrienes are compounds released by inflammatory cells within the lung and which have a powerful constricting effect upon the airways. By blocking this effect with these antagonist drugs the constriction is reversed. One of these drugs, montelukast, is presently licensed for children over two years old. Zafirlukast can be used in children over 12 years old.

    What are the long-term prospects?

  • Most children outgrow the disease.
  • The milder it is, the greater the chance of outgrowing it.


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