Factor V Leiden

Reviewed by Dr Patrick Davey, cardiologist and Dr Rachel Green, consultant haematologist

How is Factor V Leiden treated during pregnancy?
Women carrying two genes for Factor V Leiden will need to receive treatment with a heparin anticoagulant medicine during pregnancy. The same applies to women carrying just one gene for Factor V Leiden who have previously had a blood clot themselves or who have a family history of blood clots.

All women carrying a gene for Factor V Leiden may need to wear special stockings to prevent clots during the last half of pregnancy. After the birth of the child they may be prescribed the anticoagulant drug heparin.

Prognosis
The risk of developing a clot increases with age, but in a survey of people over the age of 100 who carry the gene, it was found that only a few had ever suffered from thrombosis.

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