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The deficiency occurs either through the reduced production or an increased loss of red blood cells. These cells are manufactured in the bone marrow and have a life expectancy of approximately four months.
To produce red blood cells, the body needs (among other things) iron, vitamin B12 and folic acid. If there is a lack of one or more of these ingredients, anaemia will develop.
What are red blood cells?
Red blood cells are the cells that circulate in the blood plasma (fluid) and give blood its red colour. Through its pumping action, the heart propels the blood around the body through the arteries. The red blood cells obtain oxygen in the lungs and carry it to all the body's cells.
The cells use the oxygen to fuel the combustion (burning) of sugar and fat, which produces the body's energy.
During this process, called oxidation, carbon dioxide is created as a waste product. It binds itself to the red blood cells that have delivered their load of oxygen. The carbon dioxide is then transported via the blood in the veins back to the lungs where it is exchanged for fresh oxygen by breathing.
Causes of anaemia during pregnancy
Women often become anaemic during pregnancy because the demand for iron and other vitamins is increased. The mother must increase her production of red blood cells and, in addition, the foetus and placenta need their own supply of iron, which can only be obtained from the mother.
In order to have enough red blood cells for the foetus, the body starts to produce more red blood cells and plasma. It has been calculated that the blood volume increases approximately 50 per cent during the pregnancy, although the plasma amount is disproportionately greater. This causes a dilution of the blood, making the haemoglobin concentration fall. This is a normal process, with the haemoglobin concentration at its lowest between weeks 25 and 30. The pregnant woman may need additional iron supplementation, and a blood test called serum ferritin is the best way of monitoring this.
Other causes include:
What are the symptoms of anaemia during pregnancy?
If the woman is otherwise healthy, she will rarely have any symptoms of anaemia unless her haemoglobin (red pigment) is below 8g/dl.
What can be done to avoid anaemia during pregnancy?
How does a doctor diagnose anaemia during pregnancy?
Apart from the clinical symptoms, anaemia is usually detected during antenatal screening. Blood tests are usually done at the first consultation, and again in the second half of pregnancy.
A description of the red blood cells - their different form and colour will be included in the result of the blood test.
In women of Afro-Caribbean or Mediterranean origin, additional tests are performed to screen for genetic causes of anaemia, namely sickle cell anaemia and thalassaemia.
Possible complications of anaemia
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